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. 2023 Aug 19;27(9):4877–4896. doi: 10.1007/s00784-023-05050-x

Table 4.

Overview of the characteristics of the included studies

Study Setting Materials Evaluation criteria No of patients No of teeth Type of restoration Evaluated teeth. Restoration material Cementation material Follow-up (y) Dropout (%) Survival (%) Type of failure
RCT
  Aslan et al. (2019) University LD. IC Modified USPHS

35

M: 12

W: 23

75

Pr: 15

Mo: 60

Inlay: 22

Onlay: 53

25 LD: IPS e.max CAD DC. Variolink Esthetic 1 mn 0 100
25 GC: lithium aluminosilicate DC. Variolink Esthetic 1 mn 0 100
25 IC: Cerasmart DC. Variolink Esthetic 1 mn 0 100
  Coşkun et al. (2020) University LD. IC Modified USPHS

14

M: 8

F: 6

60

Pr: 10

Mo: 60

Inlay: 4

Onlay: 56

30 LD: IPS e.max CAD DC. Variolink Esthetic 2 mn 0 100
30 IC: Cerasmart DC. Variolink Esthetic 2 mn 0 100
  Souza et al. (2021) University LD. IC FDI

20

M: 15

F: 5

Pr: 4

Mo: 16

Onlay: 40 20 LD: IPS e.max CAD DC. RelyX Ultimate 1 mn 0 100

Pr: 0

Mo:20

20 IC: Lava Ultimate CAD DC. RelyX Ultimate 1 mn 0 100
  Fasbinder et al. (2020) University L. IC Modified USPHS

86

M: 30

F: 56

120

Pr: 38

Mo: 82

Onlay: 120 60 L: IPS Empress CAD DC. RelyX ultimate. Variolink II 5 mn 0 91.7

4 restoration fracture

1 restoration chipping

60 IC: Lava Ultimate CAD DC. RelyX ultimate. Variolink II 5 mn 0 90

2 endodontic treatment

2 tooth fracture

1 restoration fracture

1 restoration chipping

  Molin & Karlsson (2000) University L. G CDA

20

M: 9

F: 11

20

Pr: 11

Mo: 9

Inlay: 20

Surfaces:

2: 9

3: 11

20 L: IPS Empress DC 5 mn 0 80 4 restoration fracture

20

Pr: 14

Mo: 6

Inlay: 20

Surfaces:

2: 4

3: 16

20 G Zinc Phosphate 5 mn 0 95 1 hypersensitivity
Prospective
  Donly et al. (1999) University G. IC USPHS 18

Pr: 5

Mo: 13

Inlay: 11

Onlay: 7

18 G Zinc Phosphate 7 mn 0 83.3

x secondary caries

x tooth fracture

x restoration fracture

Pr: 18

Mo: 18

Inlay: 32

Onlay: 4

36 IC DC 7 mn 0 75

x secondary caries

x fracture of tooth-restoration interface

  Manhart et al. (2001) University. Students L. IC Modified USPHS 45

21

Pr: 8

Mo: 13

Inlay: 21. Surfaces:

1: 1

2: 4

 > 2: 16

21 L: IPS Empress DC. Sono Cem & Variolink Ultra 3 mn 0 100

37

Pr: 23

Mo: 13

Inlay: 37. Surfaces:

1: 4

2: 19

 > 2: 14

37 IC: Tetric. Blend-a-Lux & Pertac-Hybrid unifill DC. Sono Cem & Variolink Ultra 3 mn 0 89.2
  Kaytan et al. (2005) University L. IC Modified USPHS

47

M: 14

F: 33

Mo: 87 Inlay: 87 43 L: IPS Empress DC. Variolink II Low 2 mn 7.4 97.7 1 endodontic treatment
44 IC: Solidex DC. Variolink II Low 2 mn 100
  Khairallah et al. (2009) University L. IC Modified USPHS 15

18

Pr: 6

M: 12

Inlay: 18. Surfaces:

1: 2

2: 3

 > 2: 13

18 L: IPS Empress DC. RelyX ARC 6.25 mn 0 94.40

2 marginal opening

1 endodontic treatment

1 restoration fracture

18

Pr: 6

M: 12

Inlay: 18. Surfaces:

1: 3

2: 12

 > 2: 21

18 IC: Targis DC. RelyX ARC 6.25 mn 0 100
Retrospective
  Haas et al. (1992) University IC. G None 73 NS NS 30 G: Degulor C Microfill Pontic C 5 NS 100 NS
30 G: Degulor C Zinc Phosphate. Mizzy-Fleck’s 5 100
30 IC: Coltene Duo Cement 5 80
30 IC: Kulzer Microfill Pontic C 2 80
30 GC: Dicor Tulux Cement 5 93.33
  Wagner and Schmalz (2003) University L. G Modified USPHS 64

84

Pr: 16

Mo: 68

Onlay: 84 42 L: IPS Empress DC 5.25md (1–6) 0 96 2 restoration fracture
42 Gold Phosphate cement 4.75md (0.25–13.08) 0 96 2 extraction for periodontal reasons
  Bresser et al. (2019) Private practice LD. IC Modified USPHS

120

M: 42

F:78

197

Pr: 54

Mo: 143

Inlays: 9

Onlays: 188

144 LD: IPS e.max Press Heated composite. Estelite Σquick 4.8 mn 0 96.5

2 secondary caries

1 restoration fracture

53 IC: Adoro Heated composite. Estelite Σquick 4.8 mn 0 94.3

3 secondary caries

1 endodontic treatment

1 severe periodontal breakdown

NS, non-specified; LD, lithium disilicate; L, leucite; GC, glass ceramic; IC, indirect resin composite; G, gold; DC, dual cure; M, male; F = female; Pr, premolar; Mo, molar; md, median; mn, mean