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. 2023 Jul 10;160(3):223–251. doi: 10.1007/s00418-023-02209-1

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Advanced GPU Accelerated Volume Explorer (AGAVE) displaying a downsampled level from a multi-terabyte mouse brain OME-Zarr dataset. The number of pixels actually loaded is displayed at lower right. The full resolution data is 47,310 × 20,344 × 18,471 which consumes about 33 TB. The ability to quickly access multiresolution data makes low latency interactive visualization possible