Table 2.
Pathway integration by Joint-Pathway Analysis of DEGs and metabolites of LD group with controls.
Pathways in LD group | Total | Raw p | Holm adjust | FDR | Impact | Matched features |
---|---|---|---|---|---|---|
Aminoacyl-tRNA biosynthesis | 74 | 2.63 × 10−10 | 2.21 × 10−08 | 2.21 × 10−08 | 0.12329 | cpd:C00152; cpd:C00135; cpd:C00079; cpd:C00065; cpd:C00073; cpd:C00123; cpd:C00078; cpd:C00148 |
Histidine metabolism | 32 | 0.01059 | 0.87874 | 0.44466 | 0.22581 | cpd:C00135; mmu:140483 |
Cysteine and methionine metabolism | 71 | 0.04757 | 1 | 0.98896 | 0.11429 | cpd:C00065; cpd:C00073 |
(“cpd” represents “KEGG ID” whereas “mmu” represents “Entrez ID” of DEGs).