Table 1.

Observed phenotype of SLC13A5 and SLC25A1 sTg mice.

	SLC13A5OB	SLC25A1
Median lifespan	Reduced	Normal
Maximum lifespan	Reduced	Normal
Body weight	Reduced	Reduced
Hunched posture	Common	Normal
Hair loss	Pronounced	Normal
Hair regrowth	Reduced	Normal
Skin lesions	Pronounced	Normal
Wound repair	Retarded	Normal
Dermal thickness	Increased	Normal
Adipose tissue	Reduced	Reduced
Bone density	Reduced	Normal
Liver size	Normal	Reduced
Spleen size	Increased	Normal
Lymph nodes size	Increased	Normal
Gallbladder size	Normal	Enlarged
Rectal prolapse	Common	Normal
Systemic inflammation	Increased	Normal
Peripheral WBC	Neutrophilia	Normal
Peripheral RBC	Normal	Normal
Citrate (cytoplasm)	Increased	Increased
Ac-CoA (cytoplasm)	Increased	Increased
Ac-CoA (ER)	Increased	Increased
Glycemia (fasting)	Normal	Normal
Ketone bodies (fasting)	Increased	Increased
Lipid droplets (number)	Increased	Increased
Lysosome (number)	Increased	Normal
Mitochondria (surface)	Increased	Increased

WBC white blood cell count, RBC red blood cell count