Skip to main content
. 2023 Aug 10;12(16):e029466. doi: 10.1161/JAHA.122.029466

Table 2.

Multivariable Linear Regression Models to Assess Future TAA Growth Rate [log(TAA growth+1)]

Model Chronological age alone (Model's adjusted R 2=0.268) Arterial age alone (Model's adjusted R 2=0.343) Chronological age+arterial age (Model's adjusted R 2=0.354)
Variable β±SE β* P value β±SE β* P value β±SE β* P value
Chronological age, 1 y 0.0007±0.002 0.033 0.763 −0.004±0.003 −0.206 0.083
Arterial age, 1 y 0.003±0.0009 0.333 0.0003 0.004±0.001 0.420 <0.0001
Male sex (vs female sex) −0.043±0.024 −0.163 0.080 −0.043±0.023 −0.165 0.063 −0.041±0.023 −0.156 0.076
BSA, 1 m2 −0.005±0.103 −0.005 0.958 −0.010±0.092 −0.009 0.918 −0.068±0.098 −0.064 0.487
dTAA (vs hTAA) 0.029±0.025 0.118 0.249 0.002±0.022 0.009 0.926 0.015±0.023 0.056 0.474
Baseline TAA size, 1 mm 0.010±0.005 0.165 0.053 0.005±0.005 0.263 0.091 0.007±0.005 0.108 0.184
Time between studies, 1 y −0.022±0.010 0.025 −0.178 −0.027±0.009 −0.217 0.004 −0.027±0.009 −0.214 0.005
Ascending aneurysm location (vs root location) −0.376±0.075 −1.334 <0.0001 −0.367±0.070 −1.302 <0.0001 −0.349±0.070 −1.239 <0.0001
Descending aneurysm location (vs root location) 0.752±0.147 1.371 <0.0001 0.736±0.139 1.342 <0.0001 0.730±0.138 1.332 <0.0001
Concordant imaging modalities (vs discordant) −0.005±0.019 −0.019 0.800 −0.013±0.018 −0.052 0.471 −0.016±0.018 −0.064 0.374
Hypertension −0.005±0.022 −0.022 0.804 −0.020±0.021 −0.083 0.337 −0.022±0.021 −0.091 0.292
Diabetes 0.032±0.052 0.049 0.543 0.011±0.049 0.017 0.826 0.008±0.049 0.012 0.877
Ever smoking −0.007±0.019 −0.028 0.723 −0.0003±0.018 −0.012 0.871 0.003±0.018 0.014 0.857
Hyperlipidemia 0.025±0.021 −0.101 0.242 0.016±0.019 0.066 0.407 0.024±0.020 0.100 0.224
MAP, 1 mm Hg 0.0002±0.002 0.009 0.913 0.0008±0.002 0.033 0.667 0.001±0.002 0.056 0.474

BSA indicates body surface area; dTAA, degenerative thoracic aortic aneurysm; hTAA, hereditary thoracic aortic aneurysm; MAP, mean arterial pressure; and TAA, thoracic aortic aneurysm.