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. 2023 Aug 10;12(16):e029466. doi: 10.1161/JAHA.122.029466

Table 3.

Multivariable Logistic Regression Models to Assess Future Accelerated TAA Growth (Growth>Sex‐Specific Median)

Model Chronological age alone c‐statistic: 0.660 Arterial age alone c‐statistic: 0.708 Chronological age+arterial age c‐statistic: 0.728
Variable OR 95% CI P value OR 95% CI P value OR 95% CI P value
Chronological age, 5 y 0.985 0.783–1.238 0.895 0.769 0.582–1.017 0.066
Arterial age, 5 y 1.161 1.045–1.290 0.005 1.230 1.085–1.394 0.001
Male sex (vs female sex) 0.923 0.360–2.537 0.867 0.900 0.339–2.387 0.832 0.941 0.350–2.527 0.904
BSA, 1 m2 0.985 0.130–7.461 0.988 1.110 0.154–8.005 0.917 0.551 0.065–4.649 0.584
dTAA (vs hTAA) 1.011 0.388–2.632 0.983 0.593 0.285–0.227 0.285 0.781 0.286–2.137 0.631
Baseline TAA size, 1 mm 1.057 0.956–1.040 0.281 1.015 0.914–1.128 0.778 1.026 0.923–1.140 0.639
Time between studies, 1 y 0.888 0.730–1.080 0.233 0.839 0.682–1.031 0.094 0.841 0.683–1.035 0.102
Non‐root aneurysm location 1.681 0.619–4.567 0.308 1.685 0.635–4.467 0.295 2.484 0.845–7.299 0.098
Concordant imaging modalities (vs discordant) 0.771 0.365–1.626 0.494 0662 0.306–1.432 0.295 0.607 0.276–1.334 0.214
Hypertension 1.009 0.432–2.236 0.983 0.744 0.301–1.835 0.521 0.713 0.285–1.784 0.470
Diabetes 0.623 0.082–4.752 0.648 0.493 0.055–4.393 0.526 0.473 0.051–4.377 0.509
Ever smoking 1.246 0.585–2.653 0.569 1.323 0.611–2.886 0.474 1.568 0.702–3.505 0.273
Hyperlipidemia 2.396 1.046–5.487 0.039 2.066 0.906–4.710 0.085 2.579 1.081–6.154 0.033
MAP, 1 mm Hg 0.999 0.959–1.040 0.959 1.002 0.961–1.044 0.940 1.008 0.966–1.052 0.704

BSA indicates body surface area; dTAA, degenerative thoracic aortic aneurysm; hTAA, hereditary thoracic aortic aneurysm; MAP, mean arterial pressure; OR, odds ratio; and TAA, thoracic aortic aneurysm.