Figure 2. Flow and gradient classification.

Subgroups by flow/gradient classification in the entire population (A) and in the preserved and reduced EF population (B). Patients with a mean transvalvular gradient <40 mm Hg were classified as having LG AS, whereas those with a mean gradient ≥40 mm Hg were considered to have HG AS. An LVSVi <35 mL/m² was defined as LF AS, otherwise it was considered NF AS. According to the mean gradient and LVSVi status, the patients were subdivided into 4 subgroups: LF‐LG, NF‐LG, LF‐HG, and NF‐HG. When we subdivided the patients according to the flow and PG state, 143 (8%) were classified as LF‐LG, 343 (20%) as NF‐LG, 191 (11%) as LF‐HG, and 1065 (61%) as NF‐HG. AS indicates aortic stenosis; AV, aortic valve; EF, ejection fraction; HG, high‐gradient; LF, low‐flow; LG, low‐gradient; LVEF, left ventricular ejection fraction; LVSVi, left ventricular stroke volume index; NF, normal‐flow; PG, pressure gradient; and TAVI, transcatheter aortic valve implantation.