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. 2023 Jul 5;73(2):116–123. doi: 10.3164/jcbn.22-100

Fig. 5.

Fig. 5.

Inhibiting BMP/TGF-β1 signaling reversed the effects of SMOC2 on Ang II-induced VSMCs proliferation, migration and ECM degradation. (A, B) CCK-8 and Transwell assays were used to detect proliferation and migration. (C, D) The contents of MMP-2 and MMP-9 were evaluated by ELISA assay. (E, F) Western blot was employed to detect the protein expression of MMP-2, MMP-9, TIMP-1, α-SMA, OPN. One-way ANOVA was used for statistical analysis. *p<0.05 compared to Ang II group. #p<0.05 compared to Ang II + ov-SMOC2 group.