figs1.

Supplemental Figure 1. Effect of fasting on HFD mice during the light photoperiod. Left/orange: ad libitum (ad libitum) fed mice, center/red: the same animals two days later fasted at 0800 (arrow). Right: mean differences for each animal between 0800 and 0900. A) blood glucose, B) body temperature, C) metabolic rate, D) respiratory exchange ratio, E) in-cage distance traveled F) food intake. The solid black line represents the mean value at each minute, orange or red shaded area represents the SEM. ns, not significant; ∗∗∗p<0.001