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. 2023 Aug 26;77:101795. doi: 10.1016/j.molmet.2023.101795

Figure 2.

Figure 2

Fasting-induced variation in glucose tolerance testing.A–F: Recordings with continuous glucose monitoring (CGM). A) baseline glucose levels: the mean of 30 min recordings prior to GTT glucose bolus. B) Area Of the Curve (AOC) of the glucose excursion curve GEC in (D–F). C) standard deviation (SD) of AOC in B. D–F) CGM GTT during ad libitum, 4-h or 18-h fasting for n = 11 mice. G–R) Recordings with a handheld glucometer for male (G–L) and female (M–R) mice G, M) baseline glucose levels. H, N) glucose tolerance tests under ad libitum and 4-h fasted conditions, I, O) AOC of the GTT, J, P) SD of AOC. K, Q) Area under the Curve (AUC) of the GTT. L, R) SD of AUC. n = 20 mice per group. ns, not significant; ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001.