Table 4A.
Repartition of eyes according to the biological values of patients with SS sickle cell disease or SC sickle cell disease.
| Normal range | SS | SC | P-value multivariate test | P-value intersubject analysis | Cerebral vasculopathy | P-value multivariate test | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Value (SD) | Value (SD) | No | Yes | |||||||
| Value (SD) | N eyes | Value (SD) | N eyes | |||||||
| Hb | 13–16 g/L | 9.0 (1.8) | 11.7 (1.6) | < 0.001 | 0.015 | 9.4 (2.2) | 69 | 9.4 (1.6) | 24 | 0.61 |
| HbS | 0 % | 75.0 (17.2) | 49.8 (1.4) | < 0.001 | 72.6 (16.3) | 72.7 (21.0) | ||||
| Reticulocyte count |
20–80 109/L | 230.6 (136.3) | 132.0 (43.4) | 0.021 | 209.7 (112.5) | 249.0 (194.3) | ||||
| MCV | 78–98 fL | 88.7 (12.9) | 71.3 (7.2) | < 0.001 | 85.0 (13.8) | 90.2 (15.0) | ||||
| Bilirubine | < 21 mol/L | 48.7 (38.0) | 25.0 (16.9) | 0.015 | 44.5 (36.3) | 51.2 (41.8) | ||||
| LDH | < 248 UI | 411.3 (140.8) | 294.8 (77.9) | 0.009 | 401.1 (145.7) | 400.7 (115.3) | ||||
SS patients, patients with SS sickle cell disease; SC patients, patients with SC sickle cell disease; Hb, hemoglobin; HbS, hemoglobin S level; MCV, mean corpuscular volume; AST, level of aspartate aminotransferase; LDH, level of lactate dehydrogenase. The bold values indicate the statistically significant results.