Table 2.

Consistency of P53 expression between preoperative biopsy and final pathology.

Preoperative biopsy	Final pathology
Total (n=1186, overall agreement: 83.8%, kappa: 0.624)
	P53wt	P53abn	Total
P53wt	718 (60.5%)	109 (9.2%)	827 (69.7%)
P53abn	83 (7.0%)	276 (23.3%)	359 (30.3)
Total	801 (67.5%)	385 (32.5%)	1186 (100%)
D&C or Pipelle biopsy (n=652, overall agreement: 79.4%, kappa: 0.539)
	P53wt	P53abn	Total
P53wt	367 (56.3%)	76 (11.7%)	443 (67.9%)
P53abn	58 (8.9%)	151 (23.2%)	209 (32.1%)
Total	425 (65.2%)	227 (34.8%)	652 (100%)
Hysteroscopic biopsy (n=534, overall agreement: 89.1%, kappa: 0.735)
	P53wt	P53abn	Total
P53wt	351 (65.7%)	33 (6.2%)	384 (71.9)
P53abn	25 (4.7%)	125 (23.4%)	150 (28.1%)
Total	376 (70.4%)	158 (29.6%)	534 (100%)

P53abn, P53 abnormality; P53wt, P53 wild-type.