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. 2023 Aug 3;15(9):e17399. doi: 10.15252/emmm.202317399

Figure EV2. Molecular analysis of the TAZG197V mouse.

Figure EV2

  1. BN‐PAGE analysis of heart mitochondria solubilized in 1% DDM (12‐week‐old mice).
  2. Quantification of NRF2 levels on Western blot normalized to Lamin‐B1. Mean ± SEM, n = 4, unpaired t‐test: *P < 0.05.
  3. Western blot analysis of isolated mouse heart (20‐week‐old mice) mitochondria (left) and quantification (right) of CPT1 and CPT2 protein levels normalized to ATP5B. Mean ± SEM, n = 3, unpaired t‐test: *P < 0.05, **P < 0.01.
  4. Western blot analysis as in a (left) and quantification of HK2 and ENO1 normalized to ATP5B. Mean ± SEM, n = 3, unpaired t‐test: *P < 0.05, **P < 0.01.