Table 2. Examples of Pd-mediated related bioorthogonal catalytic reactions.
| Reactions | Main reaction | Catalyst | Nano materials | Organism/organelle |
|---|---|---|---|---|
| Depropargylation |
|
Pd (0) (24,26,28,33,40); Pd (II/IV) (24) | Allyl2Pd2Cl2/Pd(dba)2; Pd0-resins; AS1411@Pd@UiO-66; nanoparticles; metallopeptide 2-Pd; AuPd NPs | Hela cells; BxPC-3 cells; Mia PaCa-2 cells; HCT116 cells; Zebrafish; A549 cells |
| Dealkylation |
|
Pd (0) (25,27,29-32) | Pd0-resins; cRGDfE-PdNP; Pd-microdevices; Pd-exosomes; Lipo-Pd-pHCPT; CuS@PDA/Pd NP | HCT116 cells; BxPC-3 cells; U87-MG cells; A549 cells; MDA-MB-231 cells; Zebrafish; MCF-7 cells; Mice |
| Allylcarbamate cleavage |
|
Pd (0) (34-37) | LM-Pd; Nano-Pd; Pd-NP; PT-MNs | A549 cells; HT1080 cells; B16-F10 cells; Mice |
| Propargyl oxy-benzyl cleavage |
|
Pd (0) (38,39) | Pd0-resins; Pd-Exo | A549 cells; U87G cells; U87 cells |
| Suzuki-Miyaura |
|
Pd (0) (29,40) | cRGDfE-PdNP | U87-MG cells |
Pd, palladium; NP, nanoparticle; LM, liquid metal; PT-MNs, microneedle array patches made of PVA incorporated with Pd-TNSs (designated PT-MNs); PVA, polyvinyl alcohol.