| 1 Mental state: 1. Total endpoint scores (PANNS, high score = worse) |
1 |
|
Mean Difference (IV, Random, 95% CI) |
Subtotals only |
| 1.1 short term |
1 |
49 |
Mean Difference (IV, Random, 95% CI) |
0.70 [‐8.12, 9.52] |
| 1.2 medium term |
1 |
46 |
Mean Difference (IV, Random, 95% CI) |
‐0.10 [‐9.02, 8.82] |
| 1.3 long term |
1 |
43 |
Mean Difference (IV, Random, 95% CI) |
1.80 [‐10.04, 13.64] |
| 2 Leaving the study early |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 2.1 before beginning assigned treatment |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
7.50 [1.00, 56.44] |
| 2.2 by 6 months |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
3.05 [1.12, 8.31] |
| 2.3 due to increased psychiatric symptoms |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
2.81 [0.31, 25.58] |
| 2.4 due to EPS effects |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
0.31 [0.01, 7.40] |
| 2.5 due to weight gain and hypertension |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
2.82 [0.12, 66.62] |
| 2.6 due to participant preference |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
0.94 [0.06, 14.33] |
| 3 Hospitalisation by 6 months |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 3.1 medium term |
1 |
62 |
Risk Ratio (M‐H, Random, 95% CI) |
0.63 [0.11, 3.48] |
| 4 Adverse events: 1. Continuous outcomes (skew) |
|
|
Other data |
No numeric data |
| 4.1 Change in BMI ‐ short term (skew) |
|
|
Other data |
No numeric data |
| 4.2 Change in BMI ‐ medium term (skew) |
|
|
Other data |
No numeric data |
| 4.3 Change in BMI ‐ long term (skew) |
|
|
Other data |
No numeric data |
| 4.4 Prolactin endpoint levels (ng/mL) ‐ short term (skew) |
|
|
Other data |
No numeric data |
| 4.5 Prolactin endpoint levels (ng/mL) ‐ medium term (skew) |
|
|
Other data |
No numeric data |
| 4.6 Prolactin endpoint levels (ng/mL) ‐ long term (skew) |
|
|
Other data |
No numeric data |
| 5 Adverse events: 2. Sexual experiencesm, total endpoint (ASEX, high score = worse) |
1 |
|
Mean Difference (IV, Fixed, 95% CI) |
Subtotals only |
| 5.1 short term |
1 |
44 |
Mean Difference (IV, Fixed, 95% CI) |
1.70 [‐1.26, 4.66] |
| 5.2 medium term |
1 |
41 |
Mean Difference (IV, Fixed, 95% CI) |
1.30 [‐2.30, 4.90] |
| 5.3 long term |
1 |
40 |
Mean Difference (IV, Fixed, 95% CI) |
‐0.10 [‐4.08, 3.88] |
