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. 2016 Apr 14;2016(4):CD004161. doi: 10.1002/14651858.CD004161.pub2
Study Reason for exclusion
Agid 2010 Allocation: not a randomised controlled trial.
Bouchard 2000 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: oral risperidone versus conventional antipsychotic drugs (not depot risperidone).
Canas 2010 Allocation: not randomised; review article.
DeMartinis 2012a Allocation: randomised.
Participants: people with schizophrenia.
Intervention: not depot risperidone.
1. PF‐02545920: 5 mg and 15 mg (titrated fixed doses. 3 mg (titrated).
 2. Risperidone (oral) twice a day: 3 mg titrated.
 3. Placebo.
Eerdekens 2002 a Allocation: not randomised; open‐label.
Eerdekens 2002 b Allocation: not randomised; review.
Gallhofer 1995 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: risperidone versus haloperidol or fluphenazine, not depot risperidone.
Geffen 2012 Allocation: randomised.
 Participants: people with chronic schizophrenia.
 Intervention: BL‐1020: 10 mg/day, BL‐1020: 20 ‐ 30 mg/day, risperidone (oral): 2 ‐ 8 mg/day, placebo, not depot risperidone
Gefvert 2001 Allocation: not a randomised controlled trial.
Kogeorgos 1995 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: sulpiride or risperidone versus chlorpromazine, trifluoperazine or haloperidol, not depot risperidone.
Koola 2009 Allocation: randomised.
Participants: people with schizophrenia.
Intervention: long‐acting injectable risperidone or oral atypical antipsychotics.
Outcomes: no useable data, only levels of insight and relapse at baseline.
Lindenmayer 1995 Allocation: non‐randomised comparison of two samples taken from randomised trials.
Litman 2014 Allocation: randomised.
 Participants: people with schizophrenia.
Intervention: AZD8529 40 mg, risperidone (oral) 4 mg, or placebo, not depot risperidone.
Littrell 1999 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: risperidone versus olanzapine, not depot risperidone.
Liu 2014f Allocation: randomised.
Participants: people with early stage schizophrenia.
Intervention: minocycline or placebo, not depot risperidone.
Lloyd 2010 Allocation: not randomised.
Macfadden 2008 Allocation: randomised.
Participants: people with schizophrenia.
Interventions: 25 mg or 50 mg of risperidone depot no other comparison group (post‐hoc analysis from another study).
McClure 2009a Allocation: randomised.
Participnats: females with schizotypal personality disorder, not schizophrenia.
Pikalov 2012a Allocation: not randomised, a review of studies.
Procyshyn 2010 Allocation: non‐random, pilot study.
Ritchie 1999 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: risperidone versus olanzapine, not depot risperidone.
Robinson 2000 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: risperidone versus olanzapine, not depot risperidone.
Schmechtig 2010 Allocation: randomised.
Participants: people with subclinical levels of schizophrenia‐like symptoms
 (high schizotypy).
Intervention: nicotine, risperidone, amisulpride or placebo, not depot risperidone.
Simpson 2006 Allocation: randomised.
Participants: people with schizophrenia.
Interventions: two doses of depot risperidone, no control.
Vaughan 2000 Allocation: randomised.
 Participants: people with schizophrenia.
 Interventions: not a drug trial, study of effect of community treatment orders.
Verma 2010 Interventions: participants switched to depot risperidone with no other comparison group.
Weiden 2007 Allocation: randomised to recommendation of treatment.
Wiffen 2010 Allocation: non‐randomised; depot risperidone was the only intervention.