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. 2023 Aug 28;13:1253414. doi: 10.3389/fonc.2023.1253414

Table 1.

Comparison of clinicopathological characteristics between segmentectomy and wedge resection groups before propensity score matching.

Total n=570 Segmentectomy (n=326) Wedge resection (n=244) p valuea)
Median age (IQR), y 69 (62-74) 72 (66-78) <0.001b)
Male, No. (%) 167 (51.2) 139 (57.0) 0.176
Smoking history (+), No. (%) 175 (53.7) 143 (58.6) 0.268
Right side, No. (%) 147 (45.1) 128 (52.5) 0.090
CT Tumor size (IQR), cm 1.4 (1.2-1.7) 1.4 (1.2-1.7) 0.263b)
Tumor disappearance rate (IQR), % 30.5 (5-70) 33.5 (5-70) 0.622b)
CTR, No. (%)
 26-50
 51-99
 100
88 (27.0)
90 (27.6)
148 (45.4)
58 (23.8)
69 (28.3)
117 (48.0)
0.679
PET maxSUV value (IQR) 1.22 (0.56-2.43) 1.12 (0-2.68) 0.462b)
CEA elevation, No. (%) 52 (16.0) 50 (20.5) 0.185
Clinical stage IA2≤. No. (%) 167 (51.2) 126 (51.6) 0.933
Ly (+), No. (%) 34 (10.4) 30 (12.3) 0.505
V (+), No. (%) 46 (14.1) 46 (18.9) 0.136
Pleural invasion, No. (%) 22 (6.7) 35 (14.3) 0.004
Pulmonary metastasis, No. (%) 4 (1.2) 4 (1.6) 0.730
Adenocarcinoma, No. (%) 282 (86.5) 196 (80.3) 0.051
Pathological T1c≤, No. (%) 43 (13.2) 51 (20.9) 0.017
Pathological stage IA3≤. No. (%) 50 (15.3) 51 (20.9) 0.096
Recurrence, No. (%) 18 (5.5) 41 (16.8) <0.001
 Intrathoracic only, No. (%) 17 (5.2) 32 (13.1) 0.001
Lung 10 (3.1) 15 (6.1) 0.097
Lymph node 6 (1.8) 8 (3.3) 0.288
Surgical margin 0 5 (2.0) 0.014
Pleura 4 (1.2) 8 (3.3) 0.138
 Extrathoracic (and/or intrathoracic), No. (%) 1 (0.3) 9 (3.7) 0.003

a) Fisher’s exact test, b) Mann-Whitney U test.

CEA, carcinoembryonic antigen; CT, computed tomography; CTR, consolidation tumor ratio; IQR, interquartile range; Ly, lymphatic vessel invasion; maxSUV, maximum standardized uptake values; PET, positron emission tomography; V, blood vessel invasion.