TABLE 4.
Sensitivity, specificity, positive, and negative predictive values of IFA method, with the neutralization method used as the “gold standard”
| Antibody blend | No. of isolates with the following result:
|
Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | |||
|---|---|---|---|---|---|---|---|---|
| True positive | True negative | False positive | False negative | |||||
| Poliovirus | 68 | 195 | 0 | 25 | 73.1 | 100.0 | 100.0 | 88.6 |
| Coxsackievirus type B | 22 | 261 | 1 | 4 | 84.6 | 99.6 | 95.6 | 98.4 |
| Echovirus | 107a | 164 | 10 | 7 | 93.9 | 94.3 | 91.5 | 95.9 |
a
Including eight echovirus isolates of serotypes not in the echovirus monoclonal antibody blend.