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The role of extracellular vesicles in Huntington’s disease
| Source of EVs | Content with biomarker potential | Mouse and cell models for mechanistic studies | Downstream pathway or molecule | References |
|---|---|---|---|---|
| SH-SY5Y cells | mHTT | NA | NA | [166] |
| CAD cells | CSPα | CSPα knock-out mice | SOD-1 | [170] |
| HEK-293 cells | miR-124 | R6/2 HD mice | RE1-Silencing Transcription Factor | [171] |
NA No accessible data in the study; HEK-293 cells Human embryonic kidney 293 cells; CSPα cysteine string protein α
