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. 2023 Aug 28;17:1225836. doi: 10.3389/fnhum.2023.1225836

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Copyright © 2023 Phillips, Castro, Vas, Ferguson, Harikumar and Leal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of antidepressant type on emotional mnemonic discrimination performance in responders and non-responders. (A) Lure discrimination performance across negative, neutral, and positive stimuli for responders (R) and non-responders (NR) to selective serotonin reuptake inhibitors (SSRIs). (B) Lure discrimination performance across negative, neutral, and positive stimuli for R and NR groups to other types of antidepressants (SNRIs, NDRIs, and TCAs). (C) Negativity bias in LDI (e.g., negative – neutral / negative + neutral) across SSRI and other antidepressant groups, stratified by responder status. (D) Correlation between perceived antidepressant efficacy and negativity bias in LDI in SSRI and other antidepressant groups, stratified by responder status. Asterisks in panels (A,B) represent a significant interaction between emotion and responder status, and a significant effect of responder status in panel (C).