Table 4.
Principal component analysis to categorize contributors to bone outcomes in women (A) and men (B).
| A. Analyses in whole cohort of women | |||||
|---|---|---|---|---|---|
| Variable | PC1 | PC2 | PC3 | PC4 | PC5 |
| Percentage of variance | 40.2 | 12.4 | 9.6 | 7.6 | 6.9 |
| Cumulative percentage of variance explained | 40.2 | 52.7 | 62.2 | 69.8 | 76.7 |
| Eigenvalue | 6.04 | 1.87 | 1.44 | 1.14 | 1.03 |
| Descriptive interpretation | Body size | Lean mass | Age | Mixed | Lifestyle |
| Age | −0.006 | −0.129 | 0.682 | 0.061 | −0.101 |
| Height | 0.392 | 0.030 | −0.117 | 0.051 | −0.047 |
| Weight | 0.101 | 0.400 | −0.165 | 0.603 | −0.112 |
| BMI | 0.363 | −0.163 | −0.045 | −0.240 | 0.005 |
| Smoker | 0.016 | 0.181 | 0.091 | −0.396 | 0.562 |
| Alcohol | 0.014 | 0.159 | −0.045 | 0.241 | 0.434 |
| Total body fat | 0.364 | −0.153 | −0.167 | 0.035 | −0.043 |
| Lean body mass | 0.306 | 0.413 | 0.065 | 0.059 | −0.042 |
| Trunk fat mass | 0.379 | −0.192 | −0.123 | 0.036 | 0.023 |
| Trunk lean mass | 0.291 | 0.402 | 0.148 | −0.024 | −0.026 |
| Central fat mass | 0.348 | −0.273 | −0.004 | 0.008 | 0.106 |
| Central lean mass | 0.161 | 0.406 | 0.291 | −0.329 | 0.063 |
| VAT mass | 0.306 | −0.265 | 0.137 | 0.057 | 0.111 |
| 25OHD | −0.066 | −0.112 | −0.050 | 0.303 | 0.662 |
| eGFR | −0.064 | 0.151 | −0.554 | −0.385 | −0.028 |
| B. Analyses in whole cohort of men | |||||
|---|---|---|---|---|---|
| Variable | PC1 | PC2 | PC3 | PC4 | PC5 |
| Percentage of variance | 37.0 | 18.9 | 10.2 | 7.7 | 7.1 |
| Cumulative percentage of variance explained | 37.0 | 55.8 | 66.1 | 73.7 | 80.8 |
| Eigenvalue | 5.54 | 2.83 | 1.53 | 1.15 | 1.06 |
| Descriptive interpretation | Body size | Lean mass | Age | Alcohol | Smoking |
| Age | −0.088 | −0.164 | 0.489 | −0.247 | 0.051 |
| Height | 0.409 | 0.129 | 0.043 | −0.001 | −0.074 |
| Weight | 0.127 | 0.363 | 0.029 | 0.140 | −0.439 |
| BMI | 0.388 | −0.061 | 0.029 | −0.084 | 0.170 |
| Smoker | 0.019 | 0.111 | −0.226 | −0.296 | 0.673 |
| Alcohol | −0.015 | 0.047 | −0.171 | 0.735 | 0.288 |
| Total body fat | 0.384 | −0.190 | −0.029 | 0.006 | −0.029 |
| Lean body mass | 0.274 | 0.422 | 0.114 | −0.014 | −0.080 |
| Trunk fat mass | 0.385 | −0.223 | −0.016 | 0.032 | −0.043 |
| Trunk lean mass | 0.267 | 0.422 | 0.095 | −0.012 | 0.005 |
| Central fat mass | 0.314 | −0.332 | 0.018 | 0.080 | 0.092 |
| Central lean mass | 0.102 | 0.399 | 0.094 | −0.137 | 0.387 |
| VAT mass | 0.318 | −0.302 | 0.033 | 0.073 | 0.047 |
| 25OHD | −0.068 | 0.043 | 0.448 | 0.500 | 0.244 |
| eGFR | 0.034 | 0.058 | −0.665 | 0.051 | −0.069 |
Note: The top five components that were above the 1.0‐eigenvalue threshold, contributed almost 77% of the total variability of the bone characteristics. The top five components that were above the 1.0‐eigenvalue threshold contributed 80% of the total variability of the bone characteristics. The highest weights (>0.3) are bolded.