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. 2023 Jun 16;7(9):e10783. doi: 10.1002/jbm4.10783

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© 2023 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Fig. 5 — Dynamic histomorphometry of the distal radial metaphyseal trabecular bone. (A) Single‐labeled surfaces (sLS). (B) Double‐labeled surfaces (dLS). (C) Mineralizing surface (MS/BS). (D) Mineral apposition rate (MAR). (E) Bone formation rate (BFR/BS). Mean ± SEM shown. *p < 0.05 compared with FRC group; ^& p < 0.05 compared with HRHF‐Untreated group; ^# p < 0.05 compared with HRHF‐Rest/IgG group. n.s. = no significant difference between groups. (F) Representative images of calcein (green, injected 9 days before euthanasia) and alizarin red (injected 2 days before euthanasia) for each group, taken with a 40× objective. Scale bar (F, top left FRC panel) = 50 μm and is applicable to the other images in F.