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Insulin signaling pathway. Protein-tyrosine phosphatase 1B; PTP1B, insulin receptor substrate; IRS, ROCK, PIP, Rho-kinase; PTEN, phosphatase, phosphatidylinositol phosphate; and tension homologue deleted on chromosome 10; Pleckstrin homology domain; PDK, PH domain, GβL, phosphoinositide-dependent protein kinase; G-protein beta subunit like; mTOR, substrate; PKCλ/ζ, protein kinase C λ and mammalian target of rapamycin; AS160, 160 kDa Akt ζ; GLUT4, glucose transporter 4. 15
