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. Author manuscript; available in PMC: 2023 Sep 11.
Published in final edited form as: J Vasc Res. 2008 Sep 4;46(2):152–161. doi: 10.1159/000152351

Fig. 1.

Fig. 1.

VEGF-mediated vasodilatation responses of coronary arterioles isolated from collateral-dependent and nonoccluded myocardial regions of hearts subjected to chronic occlusion. A VEGF165-induced vasodilatation was significantly enhanced in collateral-dependent arterioles of exercise-trained compared with other treatment groups. B VEGF121-mediated vasodilatation was not altered by chronic occlusion and/or exercise training. C Enhanced VEGF165-mediated vasodilatation in the collateral-dependent arterioles of exercise-trained pigs was abolished in the presence of a synthetic peptide inhibitor of the VEGF165-neuropilin-1 interaction. SED = Sedentary; EX = exercise-trained; LAD = arterioles from nonoccluded control region; LCX = arterioles from collateral-dependent region. Values are means ± SEM of the number of animals in parentheses. * Significantly different from other treatment groups.