Table 4.
Odds ratios for 30-day postoperative complications for patients with adenocarcinoma of the pancreas undergoing a pancreaticoduodenectomy from 2015 to 2019
|
Complication
|
Neoadjuvant radiotherapy crude OR (95%CI)
|
Crude P value
|
Neoadjuvant radiotherapy adjusted OR/IRR (95%CI)
|
Adjusted P value
|
| Total operative time | 0.15 (0.13, 0.16) | < 0.001a | 1.14 (1.11,1.16)1 | < 0.001a |
| Perioperative transfusion | 1.49 (1.32, 1.69) | < 0.001a | 1.58 (1.37, 1.82)2 | < 0.001a |
| Superficial SSI | 1.13 (0.93, 1.38) | 0.217 | NP | NP |
| Organ space SSI | 0.76 (0.63, 0.91) | 0.004a | 0.80 (0.66, 0.97)3 | 0.020a |
| 30-d reoperation | 1.03 (0.80, 1.32) | 0.832 | NP | NP |
| 30-d mortality rate | 0.40 (0.21, 0.75) | 0.005a | NP | NP |
| 30-d readmission rate | 1.14 (0.98, 1.32) | 0.090 | NP | NP |
| Renal failure | 0.74 (0.37, 1.47) | 0.382 | NP | NP |
| Total hospital stay | 0.09 (0.06, 0.12) | < 0.001a | 0.99 (0.96, 1.02)4 | 0.640 |
| Drain in place on POD 30 | 0.76 (0.61, 0.99) | 0.041a | 0.82 (0.64, 1.06)5 | 0.124 |
| Pancreatic fistula | 0.47 (0.38, 0.58) | < 0.001a | 0.50 (0.40, 0.63)5 | < 0.001a |
| Delayed gastric emptying | 0.81 (0.69, 0.95) | 0.010a | 0.86 (0.72, 1.01)5 | 0.073 |
P < 0.05.
Odds ratio was adjusted for: Albumin, age, sex, race, body mass index (BMI), diabetes, dyspnea, chronic obstructive pulmonary disease (COPD), hypertension, elective surgery, wound class, biliary stent, pancreatic duct size, perioperative transfusion requirement, surgical approach, resection of artery or vein.
Odds ratio was adjusted for: Albumin, age, sex, race, BMI, diabetes, dyspnea, COPD, hypertension, elective surgery, wound class, biliary stent, surgical approach, resection of artery or vein, T-stage, N-stage.
Odds ratio was adjusted for: Age, race, BMI, diabetes, steroids, wound class, American society of anesthesiologists (ASA) class, surgical approach, resection of artery or vein.
Odds ratio was adjusted for: Age, race, BMI, diabetes, steroids, wound class, ASA class, surgical approach, resection of artery or vein, organ space infection, failure to wean off ventilator by post-operative day (POD) 30, drain in place by POD 30, return to the odds ratio within 30 d of index operation, delayed gastric emptying, T-stage, N-stage, M-stage.
Odds ratio was adjusted for: Age, race, BMI, diabetes, steroids, wound class, ASA class, surgical approach, resection of artery or vein.
IRR: Insulin receptor-related receptor; NP: Not performed; OR: Odds ratio; POD: Post-operative day; SSI: Surgical site infection.