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. 2023 Aug 27;15(8):1774–1783. doi: 10.4240/wjgs.v15.i8.1774

Table 3.

Multivariable analyses of risk prediction scores after 1 year of ursodeoxycholic acid therapy


Univariate analyses
Multivariable analyses
Prognostic score
Hazard ratio
95%CI
P value
Hazard ratio
95%CI
P value
GLOBE 1.703 1.474-1.967 < 0.001 1.582 1.029-2.433 0.037
UK-PBC 6.046 3.479-10.510 < 0.001 1.012 0.330-3.102 0.983
APRI 0.998 0.971-1.024 0.860 0.918 0.812-1.038 0.171
FIB4 1.005 0.997-1.013 0.242 1.008 0.991-1.024 0.369
ALBI 2.546 1.955-3.316 < 0.001 1.194 0.595-2.40 0.618
Mayo 1.495 1.348-1.676 < 0.001 1.022 0.697-1.497 0.913

ALBI: Albumin-bilirubin; APRI: Aspartate aminotransferase-to-platelet ratio index; CI: Confidence interval; FIB4: Fibrosis-4 index.