TABLE 2.
Summary of parameters in the simulation study.
Data distribution | Lognormal (1, 2) |
Gamma (1.07, 1) | |
Weibull (0.7, 1) | |
Sample size | 20–100 |
100–500 | |
500–1000 | |
% censored | 0–30 |
30–50 | |
50–80 | |
Statistical methods | Substitution (zero, 1/2 LOD, LOD) |
Kaplan–Meier | |
Regression on order statistics | |
MLE | |
Lognormal‐MLE | |
Gamma‐MLE | |
Weibull‐MLE | |
Summary statistics | Mean, 95th percentile |
Parameters used to identify the best fitting model when using the parametric MLE method | Akaike information criterion |
Bayesian information criterion | |
Root mean square error |
Abbreviations: LOD, limit of detection; MLE, maximum likelihood estimation.