Table 3.
Risk Factors Associated With Mortality Among Patients With AAV According to Logistic Regression Models
| Characteristic | Univariate | Multivariate | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
| Pulmonary hypertension | <.001 | <.001 | ||
| Absent | 1.00 (ref) | 1.00 (ref) | ||
| Present | 3.15 (2.37-4.18) | 1.91 (1.41-2.59) | ||
| Age (at AAV diagnosis) | 1.06 (1.05-1.08) | <.001 | 1.07 (1.05-1.08) | <.001 |
| Smoker | 1.78 (1.36-2.35) | <.001 | 1.48 (1.12-1.96) | .006 |
| ANCA status | ||||
| PR3 | 1.00 (ref) | |||
| MPO | 1.48 (1.11-1.98) | .007 | ||
| Negative | 1.28 (0.76-2.15) | .86 | ||
| Kidney involvement with AAV | 1.52 (1.16-1.98) | .002 | 1.31 (0.99-1.75) | .06 |
Abbreviations: AAV, antineutrophil cytoplasmic antibody–associated vasculitis; ANCA, antineutrophil cytoplasmic antibody; MPO, myeloperoxidase; PR3, proteinase 3; ref, reference.