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FAC. AD classifier FAC is characterized by the hypometabolism (shown in blue) in medial–frontal lobes, posterior cingulum, precuneus, inferior–parietal, and temporal lobes. Hypermetabolism (shown in red) is observed in the cerebellum, paracentral lobule, and pons in AD. The voxel-wise coefficient (voxel-weights of FAC) was z-scored to the mean and standard deviation of the whole-brain. FAC, FDG PET-based AD classifier.
