Table 7.
The Tensile Strength of Incision Wounds and Epithelialization Period After Topical Administration of an Ointment Made from Solvent Fractions of P. africana Stem Bark
| Group | Tensile Strength (Gram) | Epithelialization Period (Days) |
|---|---|---|
| Untreated control | 198.78±9.59 | – |
| Simple ointment | 226.85±6.64 | 18.5±0. 56 |
| Nitrofurazone 0.2% ointment | 387.96±7.46a,A,b,A,c,A | 14.33±0.49a,A,b,A,c,B |
| 5% (w/w) aqueous fraction | 362.7±10.91a,A,b,A,c,A | 15.5±0.42a,B,b,C |
| 10% (w/w) aqueous fraction | 389.8±5.68a,A,b,A,c,A | 14.16±0.49a,A,b,A,c,B |
| 5% (w/w) n-butanol fraction | 355.63±8.22a,A,b,A,c,A | 15.83±0.3a,B |
| 10% (w/w) n-butanol fraction | 371.33±9.03a,A,b,A,c,A | 15±0.36a,A,b,B,c,C |
| 5% (w/w) chloroform fraction | 277.13±8.78a,B | 17.83±0.6 |
| 10% (w/w) chloroform fraction | 280.89±9.06a,B | 17.33±0.49 |
Notes: The data are presented as mean ± SEM (n=6) and analyzed using a one-way ANOVA with a Tukey post hoc test; aAgainst control (Simple ointment), bAgainst 5% chloroform fraction, and cAgainst 10% chloroform fraction; Ap<0.001, Bp<0.01, Cp< 0.05.