Table 2.
Cluster Analysis for iAMD Versus Normal and Spatial Delineations
| Cluster Analysis | Spatial Delineations | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Quadrants, % | Eccentricity (Ring °), % | ||||||||||||||
| Clusters | Cluster Sizes (% per 69 Stimuli) | Sensitivity Differences (dB), Mean (95% CI) | Effect Size (Z-Score) | Superior | Inferior | P | Nasal | Temporal | P | 2° | 4° | 6° | 8° | 10° | P |
| 0 | 65.2% (45/69) | −0.44 (−0.97 to 0.08) | −0.45 | — | — | — | — | — | — | — | — | — | — | — | — |
| −1 | 24.6% (17/69) | −0.93 (−1.5 to −0.36)** | −1.04 | 39 | 13 | *** | 22 | 25 | 0.66 | 20 | 63 | 50 | 5 | 0 | **** |
| −2 | 10.1% (7/69) | −1.67 (−2.36 to −0.98)**** | −1.77 | 6 | 12 | 0.16 | 12 | 12 | 1 | 80 | 38 | 0 | 0 | 0 | **** |
Sensitivities (dB) are expressed as the mean difference and 95% CI. Cluster sizes are expressed as percentages (%) derived from the number of stimuli over 69 total. For spatial delineations, proportional areas per quadrant or eccentricity/ring are expressed as percentages (%) derived from the number of stimuli per cluster over the total stimuli per quadrant or eccentricity/ring. For eccentricity, proportions were compared collectively among the 2°, 4°, 6°, 8°, and 10° rings. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
Significant differences are bolded. For multiple comparisons with significant differences (i.e., comparison between eccentricities/rings), the greatest magnitude (%) is bolded.