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. 2023 May 9;77(5):729–737. doi: 10.1093/cid/ciad286

Table 2.

Cardiovascular Disease Event Risks After Starting Antiretroviral Therapy

Time Since ART Start INSTI Other ART Adjusteda Risk Difference Adjusteda
Risk Ratio
Unadjusted CVD Event Risk Adjusteda CVD Event Risk Unadjusted CVD Event Risk Adjusteda CVD Event Risk
6 months 0.28% 0.08% 0.12% 0.16% −0.08% (−0.20 to 0.19) 0.49 (0.11–3.35)
1 year 0.28% 0.17% 0.33% 0.34% −0.17% (−0.37 to 0.19) 0.49 (0.20–1.86)
2 years 0.68% 0.38% 0.54% 0.75% −0.37% (−0.72 to 0.09) 0.50 (0.28–1.17)
5 years 2.38% 1.32% 1.51% 1.93% −0.61% (−1.54 to 0.22) 0.68 (0.37–1.14)
8 years 6.94% 2.64% 2.61% 3.34% −0.71% (−2.16 to 0.94) 0.79 (0.49–1.34)

Abbreviations: ART, antiretroviral therapy; CVD, cardiovascular disease; INSTI, integrase strand transfer inhibitor.

Adjusted for confounding and informative censoring (refer to Methods for a detailed list of covariates).