Table 2.
Pre-Injury (All Mice): Ability to Progress
| Training phase(s) | Number of trials | Correct (%) | Incorrect (%) | Omitted (%) |
|---|---|---|---|---|
| 30 | 400.2 ± 120.0 | 69.6 ± 9.22 | 23.42 ± 5.13 | 6.96 ± 6.73 |
| 10 | 155.3 ± 53.0*** | 86.83 ± 6.19*** | 9.54 ± 3.34*** | 3.63 ± 4.93 |
| 4 | 170.0 ± 92.9 | 84.32 ± 7.38 | 6.79 ± 3.22 | 8.88 ± 5.66** |
| 2 | 357.3 ± 154.4*** | 79.7 ± 3.27 | 6.26 ± 2.51 | 14.08 ± 3.06** |
All animals were able to learn the touchscreen conditional learning task before injury (training phase). Twenty-four animals were trained in total and randomly assigned to sham injury or repetitive mild traumatic brain injury following training. The minimum possible number of trials needed to progress is 120, as mice needed to demonstrate 80% correct response rate over 2 days with 60 trials/day. Data are shown as mean ± standard deviation. Statistically significant difference of each phase from the preceding phase are shown (i.e., a significance marker within 10-sec phase indicates difference from 30-sec phase).
p < 0.05; **p < 0.01; ***p < 0.001.