Table 2.
Computed tomography data of the study patients
| Variable | Training cohort (n = 181) | Internal validation cohort (n = 100) | External validation cohort (n = 112) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Without PHLF (n = 116) | With PHLF (n = 65) | p value | Without PHLF (n = 71) | With PHLF (n = 29) | p value | Without PHLF (n = 80) | With PHLF (n = 32) | p value | |
| Liver cirrhosis (N) | 50 (43.10%) | 23 (35.38%) | 0.310 | 22 (30.99%) | 7 (24.14%) | 0.493 | 34 (42.50%) | 12 (37.50%) | 0.627 |
| Ascites (N) | 11 (9.48%) | 5 (7.69%) | 0.684 | 8 (11.27%) | 1 (3.45%) | 0.393 | 8 (10.00%) | 4 (12.50%) | 0.961 |
| CT-derived ECV | 25.83 (23.26, 28.08) | 29.78 (26.41, 32.94) | < 0.001* | 25.64 (23.25, 30.15) | 31.03 (27.67, 34.93) | < 0.001 | 26.03 (22.94, 28.11) | 28.88 (27.46, 32.40) | < 0.001 |
| TV (cm3) | 43.85 (12.85, 136.75) | 67.20 (22.75, 419.00) | 0.035* | 35.00 (8.12, 226.00) | 71.30 (24.25, 229.80) | 0.676 | 37.83 (5.41, 247.28) | 12.11 (3.96, 89.87) | 0.130 |
| TLV (cm3) | 1262.00 (1046.75, 1521.00) | 1348.00 (1205.50, 1574.00) | 0.579 | 1242.88 (1025.56, 1508.00) | 1303.00 (1112.33, 1535.00) | 0.261 | 1401.00 (1171.00, 1571.00) | 1411.50 (1255.75, 1586.25) | 0.495 |
| FLR volume (cm3) | 924.42 ± 219.33 | 794.71 ± 212.56 | < 0.001* | 874.40 ± 195.61 | 748.54 ± 213.63 | 0.005 | 956.98 ± 212.99 | 866.66 ± 151.06 | 0.031 |
| mFLR ratio (%) | 81.36 (78.26, 84.63) | 66.27 (57.22, 79.85) | < 0.001* | 81.93 (79.52, 84.43) | 61.22 (53.71, 66.05) | < 0.001 | 79.89 (76.90, 83.11) | 67.45 (61.03, 70.84) | < 0.001 |
Note: Data are presented as n (percentage), median (interquartile range), or mean ± standard deviation
Abbreviations: PHLF Posthepatectomy liver failure, CT Computed tomography, ECV Extracellular volume, TLV Total liver volume, TV Tumor volume, FLR Future liver remnant, mFLR Measured FLR
*The comparison between patients without PHLF and patients with PHLF in the training cohort. p value < 0.05 means significant