Table 2.
Statistical association between localization of the primary tumor, age, sex, histopathological data and Nectin-4 expression for all entities and for the most frequent entities salivary duct carcinoma (SaDu), mucoepidermoid carcinoma (MuEp), and adenoid cystic carcinoma (ACC)
| Variable | Mean Nectin-4 H-Score (all entities) |
p | Mean Nectin-4 H-Score (SaDu) | p | Mean Nectin-4 H-Score (MuEp) |
p | Mean Nectin-4 H-Score (ACC) |
p |
|---|---|---|---|---|---|---|---|---|
|
Parotid gland Submandibular gland |
63.3 39.8 |
0.12# |
81.7 36.3 |
0.37# | 58.1 |
75.8 49.2 |
0.31# | |
|
< 60 years > = 60 years |
63.5 57.7 |
0.60# |
94.9 73.5 |
0.56# |
63.6 38.1 |
0.24# |
75.8 44.6 |
0.57# |
|
Male Female |
57.9 64.3 |
0.48# |
76.5 84.6 |
0.84# |
37.7 66.0 |
0.33# |
63.2 72.0 |
0.78# |
|
T1/2 T3/4 |
64.4 59.8 |
0.41# |
113.2 57.8 |
0.04# |
53.9 69.5 |
0.95# |
46.9 90.2 |
0.23# |
|
N0 N+ |
56.7 74.8 |
0.08# |
133.9 68.6 |
0.049# |
56.3 72.9 |
0.40# |
56.5 97.4 |
0.20# |
|
V0 V1 |
61.1 53.9 |
0.42# |
92.1 36.6 |
0.04# |
58.3 55.6 |
0.89# |
50.0 270.0 |
0.10# |
|
Pn0 Pn1 |
55.1 70.9 |
0.17# |
137.1 64.9 |
0.03# |
57.5 56.9 |
0.78# |
93.1 65.0 |
0.11# |
|
L0 L1 |
56.2 80.2 |
0.12# |
81.9 77.1 |
1.00# |
58.9 38.8 |
0.10# |
50.0 270.0 |
0.10# |
|
ECE− ECE+ |
58.0 68.2 |
0.44# |
86.0 70.0 |
0.49# |
58.9 38.8 |
0.10# |
52.6 67.6 |
0.67# |
|
G1 G2/3 |
57.3 70.0 |
0.57# |
83.9 81.0 |
0.85# |
44.2 78.9 |
0.22# |
187.5 74.6 |
0.21# |
Significance level p < 0.05, #Mann–Whitney-U test, significant values in bold letters