Table 1.

Overall cell count and proportion in each cell type and defined subcluster

Cell type	Subcluster	Non-AF		AF		Comparison
		Count	Cell Proportion	Count	Cell Proportion	p value
Myofibroblast cells	–	133	0.010	646	0.047	0.003
Fibroblast cells	DKK3-SLF	333	0.026	5441	0.399	7.62E-05
	CD34-SLF	1663	0.134	1563	0.115	6.05E-05
	CD55-LLF	5218	0.420	61	0.004	0.002
	Total	7214	0.581	7065	0.518	0.197
Mononuclear phagocytes	M1-like F-Mφ	8	0.001	818	0.060	1.92E-06
	M2-like F-Mφ	125	0.010	201	0.014	0.005
	I-Mφ	1197	0.096	1448	0.106	0.427
	IFN-Mφ	36	0.003	29	0.002	0.001
	IR-Mφ	200	0.016	105	0.007	0.001
	S100A8/9-Mφ	229	0.018	197	0.014	0.006
	T-Mφ	635	0.051	1544	0.113	0.005
	cDC1	91	0.007	209	0.015	0.003
	cDC2	78	0.006	172	0.014	0.008
	Total	2599	0.209	4723	0.346	0.001
T cells	Naive CD4+ T cells	176	0.014	23	0.001	1.88E-06
	Natural killer T cells	49	0.004	61	0.004	0.098
	T follicular helper	159	0.013	14	0.001	0.000
	CD4+ regulatory T cells	105	0.008	16	0.001	0.045
	CD4+ T helper cells 1	143	0.012	28	0.002	0.260
	CD4+ T helper cells 17	43	0.003	22	0.001	0.232
	CD4+ T helper cells 2	82	0.007	30	0.002	0.001
	Naive CD8+ T cells	333	0.027	83	0.006	0.018
	CD8+ effector T cells	155	0.012	29	0.002	0.001
	Total	1245	0.100	306	0.022	0.054
B cell	–	503	0.041	52	0.003	0.002
Mast cell	–	231	0.019	105	0.007	0.004
Endothelial cell	–	456	0.037	711	0.052	0.005
Total		12405	1	13621	1	–