Skip to main content
. 2023 Sep 1;66:102869. doi: 10.1016/j.redox.2023.102869

Fig. 3.

Fig. 3

Quantitative proteomics reveals changes in amino acid and glutathione metabolism in congenital cataracts. (A–C) Grid visualization of downregulated DEPs identified in K6W-Ub lenses at (A) E15, (B) P1, and (C) P30 and. (D–F) Grid visualization of upregulated DEPs identified in K6W-Ub lenses at (D) E15, (E) P1, and (F) P30. Shown in columns are the top 10 associated KEGG pathways, which are ordered by p-values. KEGG pathways involved in glutathione and amino acid metabolism (highlighted in red). Rows indicate DEPs, based on comparisons of K6W-Ub relative to WT. In A-C, blue shades indicate the degree of downregulation in K6W-Ub lenses, with darker shades corresponding to more downregulation, according to the key next to each grid. In D-F, red shades indicate the degree of upregulation in K6W-Ub lenses, with darker shades corresponding to more upregulation, according to the key next to each grid. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)