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. 2023 Aug 29;14:1221493. doi: 10.3389/fimmu.2023.1221493

Figure 1.

Figure 1

Lipids associated with SARS-COV-2 infections. (A) The raw intensity of 28 subclasses of lipids in COV vs HC. (B) The raw intensity of different degrees of unsaturation for FA, GL, GP, SP, and ST classes in COV vs HC. (C) The OPLS-DA scores plot of COV vs HC. (D) the volcano plot of COV vs HC. Red dots represent the upregulated lipids (FC≥1.5, VIP≥1); blue dots represent the downregulated lipids (FC ≤ 0.67, VIP≥1); gray dots represent lipids without significant changes (0.67<FC<1.5, VIP<1). (E) The important lipids prioritized by xgboost analysis. (F) The heatmap of 50 differentially expressed lipids in COV vs HC. (G) Receiver operating characteristic (ROC) and performance of the xgboost model in the training set. (H) the raw intensity of 3-Hydroxy-decenoyl-carnitine and Lauroyl-carnitine.