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. 2023 Aug 29;14:1221493. doi: 10.3389/fimmu.2023.1221493

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Copyright © 2023 Liang, Qi, Yang, Wang, Qin, Hu, Bai, Li, Zhang and Shi

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lipids associated with asymptomatic infection of SARS-COV-2. (A) The raw intensity of 28 subclasses of lipids in AS vs HC. (B) The OPLS-DA scores plot of AS vs HC. (C) the volcano plot of AS vs HC. Red dots represent the upregulated lipids (FC≥1.5, VIP≥1); blue dots represent the downregulated lipids (FC ≤ 0.67, VIP≥1); gray dots represent lipids without significant changes (0.67<FC<1.5, VIP<1). (D) The important lipids prioritized by xgboost analysis. (E) The heatmap of 81 differentially expressed lipids in AS vs HC. (F) Receiver operating characteristic (ROC) and performance of the xgboost model in the training set. (G) the raw intensity of PC(O-20:1/20:1), PC(O-20:1/20:0) and PC(O-18:0/18:1).