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. 2023 Aug 29;14:1221493. doi: 10.3389/fimmu.2023.1221493

Figure 3.

Figure 3

Lipids associated with asymptomatic and symptomatic COVID-19. (A) The raw intensity of 28 subclasses of lipids in SM vs AS; (B) The OPLS-DA scores plot of SM vs AS. (C) the volcano plot of SM vs AS. Red dots represent the upregulated lipids (FC≥1.5, VIP≥1); blue dots represent the downregulated lipids (FC ≤ 0.67, VIP≥1); gray dots represent lipids without significant changes (0.67<FC<1.5, VIP<1). (D) The important lipids prioritized by xgboost analysis. (E) The heatmap of 65 differentially expressed lipids in SM vs AS. (F) Receiver operating characteristic (ROC) and performance of the xgboost model in the training set. (G) the raw intensity of PE(16:0/22:4) and 9,10-DiHOME.