Table 3.
Kaplan-Meier Analysis and Univariate Analyses of Prognostic Factors for OS and LRFFS of Patients with NPC
OS | LRFS | |||||||
---|---|---|---|---|---|---|---|---|
4-year rate (%) |
Mean (months) | Univariate analysis (HR; 95% CI) | p value | 4-year rate (%) | Mean (months) | Univariate analysis (HR; 95% CI) |
p value | |
Age | ||||||||
≤ 30 years | 81.6% | 45.8 | 2.40 (1.01-5.69) | 0.03 | 93.1% | 50.2 | 6.30 (1.49-26.65) | 0.04 |
> 30 years | 59.8% | 36.1 | 51.1% | 38.3 | ||||
Gender | ||||||||
Female | 70.3% | 40.7 | 1.48 (0.77-2.83) | 0.23 | 66.0% | 39.9 | 0.77 (0.37-1.63) | 0.50 |
Male | 62.4% | 37.3 | 60.6% | 42.8 | ||||
Tabaco consumption | ||||||||
No | 65.3% | 39.1 | 1.04 (0.48-2.26) | 0.90 | 64.0% | 42.2 | 1.24 (0.50-3.08) | 0.63 |
Yes | 68.2% | 38.4 | 57.7% | 40.0 | ||||
Alcohol consumption | ||||||||
No | 69.6% | 40.7 | 2.22 (1.09-4.51) | 0.02 | 68.4% | 42.9 | 2.36 (0.95-5.88) | 0.06 |
Yes | 39.8% | 27.1 | 44.4% | 33.5 | ||||
Tumor classification | ||||||||
T1-T2 | 69.9% | 39.7 | 1.21 (0.51-2.58) | 0.66 | 65.8% | 42.5 | 1.21 (0.51-2.87) | 0.66 |
T3-T4 | 64.2% | 38.4 | 61.1% | 41.5 | ||||
Lymph node status | ||||||||
N0-N1 | 87.7% | 48.8 | 4.74 (1.86-12.07) | 0.001 | 78.7% | 47.3 | 3.01 (1.20-7.53) | 0.01 |
N2-N3 | 53.7% | 33.4 | 47.6% | 38.1 | ||||
Metastasis status | ||||||||
M0 | 82.0% | 46.2 | 5.55 (2.94-10.44) | 0.000 | 64.0% | 42.8 | 1.64 (0.71-3.81) | 0.24 |
M1 | 29.4% | 19.6 | 73.6% | 31.1 | ||||
Stage of the disease | ||||||||
I-II | 91.7% | 49.4 | 6.28 (0.86-45.67) | 0.06 | 87.5% | 50.5 | 6.02 (0.80-44.97) | 0.08 |
III-IV | 62.3% | 37.5 | 57.2% | 40.2 |