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. 2023;24(5):1477–1486. doi: 10.31557/APJCP.2023.24.5.1477

Table 3.

Kaplan-Meier Analysis and Univariate Analyses of Prognostic Factors for OS and LRFFS of Patients with NPC

OS LRFS
4-year
rate (%)
Mean (months) Univariate analysis (HR; 95% CI) p value 4-year rate (%) Mean (months) Univariate analysis
(HR; 95% CI)
p value
Age
≤ 30 years 81.6% 45.8 2.40 (1.01-5.69) 0.03 93.1% 50.2 6.30 (1.49-26.65) 0.04
> 30 years 59.8% 36.1 51.1% 38.3
Gender
Female 70.3% 40.7 1.48 (0.77-2.83) 0.23 66.0% 39.9 0.77 (0.37-1.63) 0.50
Male 62.4% 37.3 60.6% 42.8
Tabaco consumption
No 65.3% 39.1 1.04 (0.48-2.26) 0.90 64.0% 42.2 1.24 (0.50-3.08) 0.63
Yes 68.2% 38.4 57.7% 40.0
Alcohol consumption
No 69.6% 40.7 2.22 (1.09-4.51) 0.02 68.4% 42.9 2.36 (0.95-5.88) 0.06
Yes 39.8% 27.1 44.4% 33.5
Tumor classification
T1-T2 69.9% 39.7 1.21 (0.51-2.58) 0.66 65.8% 42.5 1.21 (0.51-2.87) 0.66
T3-T4 64.2% 38.4 61.1% 41.5
Lymph node status
N0-N1 87.7% 48.8 4.74 (1.86-12.07) 0.001 78.7% 47.3 3.01 (1.20-7.53) 0.01
N2-N3 53.7% 33.4 47.6% 38.1
Metastasis status
M0 82.0% 46.2 5.55 (2.94-10.44) 0.000 64.0% 42.8 1.64 (0.71-3.81) 0.24
M1 29.4% 19.6 73.6% 31.1
Stage of the disease
I-II 91.7% 49.4 6.28 (0.86-45.67) 0.06 87.5% 50.5 6.02 (0.80-44.97) 0.08
III-IV 62.3% 37.5 57.2% 40.2