Table 4.

Kaplan-Meier Analysis and Univariate Analyses of Prognostic Factors for DMFS and PFS of Patients with NPC

	DMFS				PFS
	4-year rate (%)	Mean (months)	Univariate analysis (HR; 95% CI)	p value	4-year rate (%)	Mean (months)	Univariate analysis (HR; 95% CI)	p value
Age
≤ 30 years	60.5%	39.3	2.11 (1.07-4.17)	0.02	66.1%	38.4	2.35 (1.23-4.49)	0.006
> 30 years	46.6%	27.8			30.9%	25.9
Gender
Female	64.6%	37.2	1.80 (1.01-3.21)	0.04	49.2%	33.5	1.48 (0.90-2.43)	0.12
Male	47.7%	28.4			34.0%	27.6
Tabaco consumption
No	55.5%	32.7	1.30 (0.70-2.40)	0.40	38.9 %	29.4	1.07 (0.59-1.92)	0.81
Yes	46.8%	28.3			38.6 %	27.8
Alcohol consumption
No	56.9%	33.6	1.97 (1.04-3.73)	0.03	45.3%	31.0	2.14 (1.19-3.86)	0.01
Yes	34.7%	20.05			39.8%	18.2
Tumor classification
T1-T2	67.4%	37.4	1.71 (0.87-3.40)	0.11	53.4%	31.1	1.51 (0.84-2.72)	0.16
T3-T4	49.4%	29.9			39.4%	24.5
Lymph node status
N0-N1	75.4%	43.0	3.24 (1.63-6.43)	0.001	66.8%	40.9	3.35 (1.82-6.13)	0.000
N2-N3	42.7%	26.2			23.3%	23.1
Metastasis status
M0	73.4%	42.9	9.12 (5.18-16.07)	0.000	55.9%	37.7	5.33 (3.28-8.64)	0.000
M1	13.5%	7.3			10.0%	11.4
Stage of the disease
I-II	91.7%	48.9	9.88 (1.36-71.42)	0.02	91.7%	48.9	13.42 (1.85-96.98)	0.01
III-IV	48.8%	29.5			31.6%	26.5