Table 1.
Clinicopathological Characteristics of the Studied Cases of HGGs and Its Correlation with PSMA Expression in TMV
| Parameter | PSMA expression in TMV | Total number of studied cases (100%) | P value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Negative staining | Positive weak staining | Positive moderate staining | Positive strong staining | |||||||||
| Number | % | Number | % | Number | % | Number | % | |||||
| Gender | Male | 9 | 25.70 | 14 | 40.00 | 11 | 31.40 | 1 | 2.90 | 35 | **0.579 | |
| Female | 7 | 20.60 | 12 | 35.30 | 11 | 32.40 | 4 | 11.80 | 34 | |||
| Tumor site | Cerebral | Frontal | 6 | 40.00 | 5 | 33.30 | 3 | 20.00 | 1 | 6.70 | 15 | *0.266 |
| Parietal | 1 | 10.00 | 5 | 50.00 | 4 | 40.00 | 0 | 0.00 | 10 | **0.598 | ||
| temporal | 3 | 21.40 | 3 | 21.40 | 6 | 42.90 | 2 | 14.30 | 14 | |||
| Occipital | 1 | 20.00 | 3 | 60.00 | 1 | 20.00 | 0 | 0.00 | 5 | |||
| more than one lobe | 1 | 7.70 | 7 | 53.80 | 3 | 23.10 | 2 | 15.40 | 13 | |||
| Deeply seated | 4 | 40.00 | 2 | 20.00 | 4 | 40.00 | 0 | 0.00 | 10 | |||
| Cerebellar | 0 | 0.00 | 1 | 50.00 | 1 | 50.00 | 0 | 0.00 | 2 | |||
| Histological subtype | Anaplastic astrocytoma | 4 | 44.40 | 4 | 44.40 | 1 | 11.10 | 0 | 0.00 | 9 | *0.022 | |
| Anaplastic oligodendroglioma | 3 | 50.00 | 1 | 16.70 | 2 | 33.30 | 0 | 0.00 | 6 | **0.163 | ||
| Anaplastic ependymoma | 0 | 0.00 | 1 | 50.00 | 1 | 50.00 | 0 | 0.00 | 2 | |||
| classic GB | 1 | 5.00 | 6 | 30.00 | 9 | 45.00 | 4 | 20.00 | 20 | |||
| GB with oligodendroglial features | 0 | 0.00 | 5 | 62.50 | 2 | 25.00 | 1 | 12.50 | 8 | |||
| Recurrent GB | 4 | 36.40 | 4 | 36.40 | 3 | 27.30 | 0 | 0.00 | 11 | |||
| Gliosarcoma | 4 | 30.80 | 5 | 38.50 | 4 | 30.80 | 0 | 0.00 | 13 | |||
| Histological grade | III | 7 | 41.20 | 6 | 35.30 | 4 | 23.50 | 0 | 0.00 | 17 | *0.054 **0.191 | |
| IV | 9 | 17.30 | 20 | 38.50 | 18 | 34.60 | 5 | 9.60 | 52 | |||
*P-value according to positivity and negativity; ** P-value according to composite PSMA score; Chi square test