Table 3.
Comparison between PSMA Expression in TMV and TC according to Histological Grade and Histological Subtype
| Tumor parameter | PSMA expression in TMV | PSMA expression in tumor cells | Total number of studied cases | P- value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | ||||||||
| Number | % | Number | % | Number | % | Number | % | -100% | |||
| Tumor grade | III | 10 | 58.80 | 7 | 41.20 | 12 | 70.60 | 5 | 29.40 | 17 | *0.473 |
| **0.476 | |||||||||||
| IV | 43 | 82.70 | 9 | 17.30 | 27 | 51.90 | 25 | 48.10 | 52 | *<0.001 | |
| **<0.001 | |||||||||||
| Tumor histological subtype | Anaplastic astrocytoma | 5 | 55.60 | 4 | 44.40 | 7 | 77.80 | 2 | 22.20 | 9 | *0.620 |
| **0.793 | |||||||||||
| Anaplastic oligodendroglioma | 3 | 50.00 | 3 | 50.00 | 3 | 50.00 | 3 | 50.00 | 6 | *1 | |
| **1 | |||||||||||
| Anaplastic ependymoma | 2 | 100.00 | 0 | 0.00 | 2 | 100.00 | 0 | 0.00 | 2 | *… | |
| **1 | |||||||||||
| GB | 19 | 95.00 | 1 | 5.00 | 18 | 90.00 | 2 | 10.00 | 20 | *1 | |
| **0.036 | |||||||||||
| GB with oligodendroglial features | 8 | 100.00 | 0 | 0.00 | 3 | 37.50 | 5 | 62.50 | 8 | *0.026 | |
| **0.032 | |||||||||||
| Recurrent GB | 7 | 63.60 | 4 | 36.40 | 4 | 36.40 | 7 | 63.60 | 11 | *0.201 | |
| **0.196 | |||||||||||
| Gliosarcoma | 9 | 69.20 | 4 | 30.80 | 2 | 15.40 | 11 | 84.60 | 13 | *0.005 | |
| **0.011 | |||||||||||
*P-value according to positivity and negativity; ** P-value according to composite PSMA score; Chi square test