Table 1.

Distribution Comparisons of Selected Demographic and Clinicopathological Characteristics of Breast Cancer Cases and Healthy Controls from Rural Areas of Maharashtra

Variable	Cases (N=400)		Controls (N=400)		p-Value based
	No.	(%)	No.	(%)	on χ2
Age (Mean ± SD) years	52.43 ±12.37		42.37 ± 13.90
≤ 40	78	19.5	207	51.75	0.001
>40	322	80.5	193	48.25
Tobacco smoking Status
Tobacco users	219	54.75	113	28.25	0.001
Tobacco no users	181	45.2	287	71.75
Diet
Vegetarian	84	21	118	29.5	0.006
Mixed	316	79	282	70.5
Education
High School	66	16.5	108	27	0.001
High School graduate (12 y)	53	13.25	50	12.5
College /Graduate	20	5	128	32
No School	261	65.25	114	28.5
Economic status
Poor	295	73.75	271	67.75	0.001
Middle	105	26.25	129	32.25
Age @ Ist delivery (yrs)
(Mean Age ± SD)	19.63 ± 2.66		21.06 ± 3.55
≤20	218	54.5	183	45.75	0.001
>20	182	45.5	217	54.25
Family history of Cancer
Yes	100	25	10	2.5
No	300	75	390	97.5
Tumor localization			p-value =0.01
Left breast	213	53.25
Right breast	185	46.25
Right + Left breast	2	0.5
Hormone Status			p-value< 0.001
ER+ve	218	54.5
ER-ve	182	45.5
PR+ve	197	49.25
PR-ve	203	50.75
Her2 +ve	57	14.25
Her2 -ve	343	85.75
ER/PR/Her2+ve	8	2
ER/PR/Her2-ve	134	33.5
Histological Subtypes			p-value <0.001
Invasive ductal Carcinoma	299	74.75
Lobular Carcinoma	15	3.75
Mucinous Carcinoma	12	3
Medulary Carcinoma	27	6.75
Invasive Apocrine Carcinoma	12	3
Others	35	8.75
Histological Grade			p-value= 0.147
I, II	195	48.75
III, IV	205	51.25
Tumor size in cm			p-value=0.001
≤ 2	180	45
> 2	220	55

Significance p< 0.005