Table 5.

Multivariate analysis of change in eGFR over 2-year follow-up with generalized linear mixed models

Variables	Coefficient	95% CI		P value
Historical eGFR declinea	−20.2	−25.1	−15.3	0.001
MIC (Ref: 1A–1B)
1C	−3.1	−6.8	0.6	0.078
1D–1E	−4.9	−9.3	−0.6	0.034
Age groups (Ref: ≤ 30 yrs)
31–40	−3.5	−8.6	1.7	0.179
41–50	−4.8	−10.1	0.6	0.075
≥ 51	−6.9	−12.8	−1.1	0.025

CI, confidence interval; eGFR, estimated glomerular filtration rate; MIC, mayo imaging classification.

Adjusted for Historical eGFR decline, MIC, age group, chronic kidney disease stage, gender, family history of ADPKD reaching end-stage kidney disease, systolic blood pressure diastolic blood pressure, diabetes mellitus, PKD mutation

^aeGFR decline <5 ml/min/1.73 m² in one year or <2.5 ml/min/1.73 m² in per over 5 years.