Table 4.
Factors associated with NAFLD (CAP ≥263 dB/m) in univariate and multivariable analyses
| Univariate analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| Variables | OR | CI | P-Value | OR | CI | P-Value |
| Age | 1.04 | 1.02-1.06 | <0.01 | 1.04 | 1.01-1.08 | 0.02 |
| Gender | ||||||
| Male | Reference | |||||
| Cisgender Female | 1.71 | 0.96-3.07 | 0.97 | |||
| Transgender female | 0.91 | 0.40-2.06 | 0.96 | |||
| Race | ||||||
| White | Reference | |||||
| Black | 0.36 | 0.22-0.59 | 0.01 | 0.42 | 0.19-0.92 | 0.03 |
| Other | 0.60 | 0.28-1.33 | 0.98 | 0.52 | 0.14-1.87 | 0.31 |
| Ethnicity | ||||||
| Hispanic or Latino | 1.66 | 0.99-2.74 | 0.97 | |||
| Non-Hispanic | Reference | |||||
| Study site | ||||||
| Indiana | Reference | |||||
| Massachusetts | 1.91 | 1.10-3.31 | 0.02 | 2.42 | 0.92-6.39 | 0.08 |
| Texas | 1.93 | 1.12-3.33 | 0.02 | 3.35 | 1.31-8.60 | 0.01 |
| Waist circumference, cm | 1.10 | 1.08-1.13 | <0.01 | 1.05 | 0.99-1.10 | 0.04 |
| BMI | 1.25 | 1.18-1.33 | <0.01 | |||
| Diabetes Mellitus | ||||||
| No | Reference | |||||
| Yes | 3.30 | 1.50-7.29 | <0.01 | 3.20 | 1.02-10.07 | 0.04 |
| ALT | 1.05 | 1.03-1.07 | <0.01 | 1.05 | 1.01-1.08 | 0.01 |
| AST | 1.04 | 1.02-1.06 | <0.01 | |||
| Platelets | 1.00 | 0.99-1.01 | 0.48 | |||
| Triglycerides | 1.01 | 1.00-1.01 | <0.01 | |||
| Fasting glucose | 1.03 | 0.99-1.06 | 0.14 | |||
| Insulin | 1.05 | 1.02-1.08 | <0.01 | |||
| HOMA-IR | 2.05 | 1.20-3.53 | 0.01 | |||
| Current CD4 | 1.00 | 1.00-1.002 | 0.02 | |||
| Nadir CD4 | 0.99 | 0.99-1.00 | 0.06 | |||
| Current ART | 3.25 | 0.86-12.25 | 0.08 | |||