. 2023 Aug 9;6(9):1266–1274. doi: 10.1021/acsptsci.3c00071

Table 2. Summary of the Potency (EC₅₀) and Efficacy (E_max) of the Reference Inverse Agonist PSB-10, MRS7799, and MRS7907 in the GloSensor cAMP Assay^a.

	EC₅₀ (nM) (95% CI)	E_max (%) (95% CI)
PSB-10	9.41 (0.34–156)	98.4 (68.2–136)
MRS7799	2.24 (0.10–46.6)	92.5 (70.7–116)
MRS7907	91.3 (25.3–259)	203 (175–233)

Data are from four independent experiments, each performed in duplicate. The E_max of PSB-10 is used as 100% in each independent experiment. Final curves are fit through the mean of the normalized values from the independent experiments, resulting in values slightly deviating from 100%.

Table 2. Summary of the Potency (EC50) and Efficacy (Emax) of the Reference Inverse Agonist PSB-10, MRS7799, and MRS7907 in the GloSensor cAMP Assaya.

Table 2. Summary of the Potency (EC₅₀) and Efficacy (E_max) of the Reference Inverse Agonist PSB-10, MRS7799, and MRS7907 in the GloSensor cAMP Assay^a.