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Genes with high cis proportion show evidence of relaxation of constraint. Boxplot showing the distribution of A percent coding identity B dN/dS or C LOEUF for genes with a high, moderate, or low cis proportion. Boxplots showing diploid expression relative to mean human expression in select cell types for D CLDN4 or E CEPBA. Adjacent heatmaps show the median diploid expression across all samples from both species
