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. 2023 Sep 12;18:60. doi: 10.1186/s13024-023-00647-y

Fig. 5.

Fig. 5

Longitudinal linear mixed-effects model analyses evaluating the relationship between PET tracers’ binding/uptake and plasma GFAP. (A, B) Scatterplots for composite cortical ROIs and (C, D) surface maps where cortical ROIs with a significant longitudinal association between PET tracers’ binding/uptake and plasma GFAP are depicted in colour. The estimate (Est.), the standard error (parentheses) and p value of the models are shown. NC: non-carriers; pMC: presymptomatic mutation carriers; sMC: symptomatic mutation carriers